Chaitanya et al., Neurochem Res 2008
(Brain Ischemia) :
Activation of calpain , cathepsin-b and caspase-3 during transient focal cerebral ischemia in rat model
Yamashima et al., Eur J Neurosci 1998
(Ischemic Attack, Transient) :
These observations indicate that calpain induced cathepsin B release is crucial for the development of the ischaemic neuronal death, and that a specific inhibitor of cathepsin B is of potential therapeutic utility in ischaemic injuries to the human CNS