Gene interactions and pathways from curated databases and text-mining

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CTSD — IGF2

Text-mined interactions from Literome

De León et al., Horm Metab Res 1999 (Breast Neoplasms) : In our present study, we transfected antisense IGF-II into IGF-II secreting MCF-7 cells to test the hypothesis that blocking IGF-II may reduce the secretion of cathepsin D in breast cancer cells
Vyas et al., Growth Factors 2006 (Breast Neoplasms...) : Insulin-like growth factor II mediates resveratrol stimulatory effect on cathepsin D in breast cancer cells
Rochefort et al., C R Seances Soc Biol Fil 1991 (Breast Neoplasms...) : In MCF7 cells, cathepsin D is specifically and directly induced by estrogens and also induced by growth factors ( EGF, IGF-I and bFGF ), but this induction is dependent upon de novo protein synthesis