Gene interactions and pathways from curated databases and text-mining

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CXCL10 — EGF

Text-mined interactions from Literome

Shiraha et al., J Cell Biol 1999 : We report here that IP-10 inhibited EGF- and heparin binding EGF-like growth factor induced Hs68 human dermal fibroblast motility in a dose dependent manner ( to 52 % and 44 %, respectively, at 50 ng/ml IP-10 ), whereas IP-10 had no effect on either basal or EGFR mediated mitogenesis ( 96 +/- 15 % at 50 ng/ml ) ... IP-10 also prevented EGF- induced calpain activation ( reduced by 71 +/- 7 % )
Azenshtein et al., Cancer Lett 2005 (Breast Neoplasms...) : EGF potently up-regulated CXCL8 secretion by breast tumor cells, and its effect was promoted by a consecutive treatment of the cells by estrogen and progesterone
Haim et al., Neoplasia (New York, N.Y.) 2011 (Breast Neoplasms) : We found that stimulation by EGF alone induced the release of CXCL8 through signaling pathways involving ErbB2, ErbB1, Erk, and phosphoinositide 3-kinase (PI3K)
Son et al., Journal of inflammation (London, England) 2013 : Finally, CCL20 and CXCL8 responded synergistically in response to EGF and TNF in OVCAR-3 and SKOV-3 cells