Gene interactions and pathways from curated databases and text-mining

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CYCS — PARP2

Text-mined interactions from Literome

Ryan et al., J Biochem Mol Toxicol 2004 : Cytochrome c together with Apaf-1 causes activation of the initiator caspase, caspase-9, which in turn activates caspase-3 ultimately leading to the degradation of poly ( ADP-ribose ) polymerase ( PARP )
Bhattacharya et al., Biochem Pharmacol 2010 : Cytochrome c release was followed by the activation of caspase-9, caspase-3 and caspase-7, and cleavage of PARP in both MOLT-3 and K562 cells