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CYP3A4 — PCNA

Text-mined interactions from Literome

Lin et al., J Biol Chem 2008 (Liver Neoplasms) : Here we report that inhibition of cyclin dependent kinases (Cdks) by kenpaullone and roscovitine ( two small molecule inhibitors of Cdks that we identified in a screen for compounds that activate hPXR ) leads to activation of hPXR mediated CYP3A4 gene expression in HepG2 human liver carcinoma cells
Pondugula et al., Drug Metab Dispos 2010 (Liver Neoplasms) : We have recently shown that cyclin dependent kinase 2 (CDK2) negatively regulates hPXR mediated CYP3A4 gene expression