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DCN — IL10
Text-mined interactions from Literome
Yamamoto et al., Biochem Biophys Res Commun 2001
(Scleroderma, Localized) :
Effect of
interleukin-10 on the gene expression of type I collagen, fibronectin, and
decorin in human skin fibroblasts : differential regulation by transforming growth factor-beta and monocyte chemoattractant protein-1 ... Response to
IL-10 by scleroderma fibroblasts was similar to that in normal dermal fibroblasts, with decreased expression levels of collagen and fibronectin and
induced decorin mRNA levels
Strazynski et al., J Biol Chem 2004
:
These data show that
IL-10 and IL-6
induce decorin mRNA transcription, but additional signals from the extracellular matrix are necessary for its translation