Gene interactions and pathways from curated databases and text-mining

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DTX1 — EP300

Pathways - manually collected, often from reviews:

  • OpenBEL Selventa BEL large corpus: ASCL1 → Complex of DTX1-EP300 (decreases, DTX1/EP300 Activity) Yamamoto et al., J Biol Chem 2001*
    Evidence: Through its binding to p300, DTX1 inhibited transcriptional activation by the neural-specific helix-loop-helix-type transcription factor MASH1, and this mechanism is likely responsible for the differentiation inhibition of neural progenitor cells.

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *