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E2F1 — GRAP2
Text-mined interactions from Literome
Kishore et al., Circ Res 2003
:
In this study, we report that c-Jun N-terminal kinase (JNK) 1 and
p38 mitogen activated protein kinases ( MAPKs ) are differentially
required for
E2F1 expression and activity in ECs
de Olano et al., Mol Cancer Res 2012
:
Consistently, studies using pharmacologic inhibitors, siRNA knockdown, and knockout mouse embryonic fibroblasts (MEF) revealed that p38 mediates the E2F1 induction by epirubicin and that the
induction of
E2F1 by
p38 is, in turn, mediated through its downstream kinase MK2 [ mitogen activated protein kinase ( MAPK) activated protein kinase 2 ; MAPKAPK2 ]