Gene interactions and pathways from curated databases and text-mining

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ECM1 — FGF16

Text-mined interactions from Literome

Nur-E-Kamal et al., Mol Cell Biochem 2008 : Activation of fibroblast growth factor receptors ( FGFRs ) requires the formation of a ternary complex between fibroblast growth factors ( FGFs ), FGFRs, and heparan sulfate proteoglycans, which are all located on the cell surface and the basement membrane ( BM ) /extracellular matrix ( ECM )
Uchii et al., Arthritis Res Ther 2008 (Disease Models, Animal...) : In cultured chondrocytes, FGF8 induced the release of matrix metalloproteinase 3 and prostaglandin E2, and caused degradation of the ECM
Etheredge et al., Invest Ophthalmol Vis Sci 2009 : The effects of IGF-I, TGF-beta1, FGF-2 , and PDGF on proliferation and ECM production by primary cultured bovine keratocytes were evaluated
Hitraya et al., Lab Invest 1995 : Heparin alone decreased the mRNA levels for these genes by 60, 77, and 65 %, respectively ; however, FGF potentiated the negative effect of heparin on ECM gene expression