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ECM2 — FGF1

Text-mined interactions from Literome

Nur-E-Kamal et al., Mol Cell Biochem 2008 : Activation of fibroblast growth factor receptors ( FGFRs ) requires the formation of a ternary complex between fibroblast growth factors ( FGFs ), FGFRs, and heparan sulfate proteoglycans, which are all located on the cell surface and the basement membrane ( BM ) /extracellular matrix ( ECM )
Uchii et al., Arthritis Res Ther 2008 (Disease Models, Animal...) : In cultured chondrocytes, FGF8 induced the release of matrix metalloproteinase 3 and prostaglandin E2, and caused degradation of the ECM
Etheredge et al., Invest Ophthalmol Vis Sci 2009 : The effects of IGF-I, TGF-beta1, FGF-2 , and PDGF on proliferation and ECM production by primary cultured bovine keratocytes were evaluated
Hitraya et al., Lab Invest 1995 : Next we studied the separate effect of heparin and aFGF or bFGF on the expression of ECM genes in HDMVEC ... Heparin alone decreased the mRNA levels for these genes by 60, 77, and 65 %, respectively ; however, FGF potentiated the negative effect of heparin on ECM gene expression ... The data also demonstrate that heparin, ECGF supplement, aFGF , and bFGF regulate ECM gene expression in HDMVEC in vitro and suggest that these growth factors may modulate the expression of matrix genes in vivo