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EDN2 — RHOA

Text-mined interactions from Literome

Morishita et al., J Neurochem 2007 : Whereas endothelin consistently activated RhoA , TGF-beta did not, and a specific inhibitor of TGF-beta type I receptor blocked TGF-beta enhanced SMA promoter activity, suggesting involvement of Smad phosphorylation
Nakaoka et al., J Mol Cell Cardiol 2010 (Cardiomegaly) : In neonatal rat cardiomyocytes, endothelin-1 (ET-1), a GPCR agonist, but not leukemia inhibitory factor (LIF), an IL-6 related cytokine, induced RhoA activation and promotes alpha-SKA gene expression via RhoA
Wang et al., Am J Physiol 1998 : Immunoprecipitation and immunoblotting revealed one form of 21-kDa Rho A that translocated from the cytosol to the membrane in response to stimulation by either endothelin ( 10 ( -7 ) M ) or ceramide ( 10 ( -7 ) M ) ( approximately 30 % increase at 30 s that was sustained at 4 min )