Gene interactions and pathways from curated databases and text-mining

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EDN2 — TGFB1

Text-mined interactions from Literome

Simonson et al., J Lab Clin Med 1992 : The fact that endothelin secretion is stimulated by cytokines, growth factors, and transforming growth factor beta is consistent with this role
Tokito et al., FEBS Lett 1991 (Adenocarcinoma...) : Production of immunoreactive ( ir- ) endothelin-2 (ET-2) in renal adenocarcinoma cells, ACHN, was reduced by transforming growth factor-beta , basic fibroblast growth factor, transforming growth factor-alpha and, most strikingly, by epidermal growth factor (EGF)
Jain et al., Am J Respir Cell Mol Biol 2007 (Lung Injury...) : Endothelin-1 induces alveolar epithelial-mesenchymal transition through endothelin type A receptor mediated production of TGF-beta1
Rieder et al., Klin Wochenschr 1991 : In the presence of transforming growth factor beta a dose dependent increase of immunoreactive endothelin release was measured
Kurihara et al., Biochem Biophys Res Commun 1989 : An enzyme linked immunosorbent assay revealed that the levels of endothelin in endothelial cell conditioned media was also increased by TGF-beta 1 ... These results suggest that TGF-beta 1 , secreted by activated platelets, is involved not only in wound healing, but in the regulation of local vascular tone by stimulating endothelin production in the endothelial cells
Schnermann et al., Endocrinology 1996 : Regulation of endothelin production and secretion in cultured collecting duct cells by endogenous transforming growth factor-beta