Gene interactions and pathways from curated databases and text-mining

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EGF — SST

Text-mined interactions from Literome

Bachwich et al., Mol Endocrinol 1992 : Somatostatin inhibits EGF stimulation of gastrin gene expression, which is in part mediated at the level of transcriptional regulation as somatostatin inhibits EGF stimulation of gastrin reporter gene constructs
Zandomeneghi et al., Regul Pept 1990 : Role of vasoactive intestinal polypeptide (VIP) and endogenous somatostatin on the secretion of epidermal growth factor (EGF) : studies on duodenal tissue cultures
Watt et al., J Neurooncol 2010 (Glioma) : The antiproliferative effect of tandem somatostatin receptor (SSTR) activation, epidermal growth factor receptor (EGFR) inhibition , and induction of DNA damage was analyzed using octreotide ( OCT ), a SSTR agonist, the clinical DNA methylating agent temozolomide ( TMZ ), Iressa, an EGFR inhibitor, and dual EGFR-DNA targeting agents termed `` combi-molecules ''
Kirkegaard et al., Gut 1984 : Effect of vasoactive intestinal polypeptide and somatostatin on secretion of epidermal growth factor and bicarbonate from Brunner 's glands ... The effect of VIP and somatostatin on secretion of epidermal growth factor and bicarbonate from Brunner 's glands was investigated in the rat
Olsen et al., Dig Dis Sci 1994 : Effect of secretin and somatostatin on secretion of epidermal growth factor from Brunner 's glands in the rat ... The effect of secretin and somatostatin on secretion of epidermal growth factor (EGF) from Brunner 's glands was investigated in rats
Grupcev et al., Regul Pept 1994 : Transforming growth factor-alpha and epidermal growth factor inhibit gastric acid secretion and stimulate release of somatostatin and neurotensin in the conscious rat ... At the highest doses, TGF alpha and EGF caused 194 % and 698 % increase of somatostatin-like immunoreactivity ( SOM-LI ) in plasma, respectively ( each P < 0.05 )