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EGF — YWHAB

Text-mined interactions from Literome

Antonelli et al., Mol Biol Cell 2000 : In Chinese hamster ovary cells, EGF receptors activate B-Raf but not Raf-1 or A-Raf
Guan et al., J Biol Chem 2000 : Furthermore, expression of Akt inhibits epidermal growth factor induced B-Raf activity and inhibition of Akt with LY294002 up-regulates B-Raf activity, suggesting that Akt negatively regulates B-Raf in vivo
Piiper et al., Mol Pharmacol 2000 : In contrast, PTx, CCK, and EGF had only minor effects on A-Raf and B-Raf activity
Ren et al., Proc Natl Acad Sci U S A 2007 : Our data identify a previously unrecognized interaction between IQGAP1 and B-Raf and suggest that IQGAP1 is a scaffold necessary for activation of B-Raf by EGF
Yamaguchi et al., American journal of physiology. Renal physiology 2010 (Polycystic Kidney, Autosomal Dominant) : We found that nanomolar concentrations of Sorafenib reduced the basal activity of ERK, inhibited cAMP dependent activation of B-Raf and MEK/ERK signaling, and caused a concentration dependent inhibition of cell proliferation induced by cAMP, epidermal growth factor , or the combination of the two agonists