Gene interactions and pathways from curated databases and text-mining

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EGFR — KRT8

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Cheng et al., Cell Growth Differ 1993 : Epidermal growth factor receptor ligands regulate keratin 8 expression in keratinocytes, and transforming growth factor alpha mediates the induction of keratin 8 by the v-rasHa oncogene
Jiang et al., Proc Natl Acad Sci U S A 1993 : We have analyzed the effects of EGFR activation on keratin gene transcription by transfecting DNAs containing keratin promoters linked to a reporter gene into primary cultures of human epidermal keratinocytes in the presence or absence of EGF or transforming growth factor alpha ( TGF alpha ), two growth factors that activate EGFR