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Price-Schiavi et al., Int J Cancer 2002
(Adenocarcinoma...) :
Overexpression of Muc4/SMC does not affect the level of ErbB2 expression in either cell line, but it does reduce binding of a number of anti-ErbB2 antibodies, including Herceptin
Jepson et al., Oncogene 2002
:
In the present study we show that Muc4/SMC alone robustly induces the phosphorylation of ErbB2 to enhance the tyrosine phosphate epitope ( Tyr1248 ) recognized by anti-phospho-ErbB2