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ESR1 — GNRH1
Text-mined interactions from Literome
Chen et al., Mol Cell Endocrinol 1999
:
Estrogen receptor mediated repression of
gonadotropin releasing hormone ( gnRH ) promoter activity in transfected CHO-K1 cells ... Results of this study demonstrated that
estrogen receptor can
mediate the negative feedback regulation of human
GnRH upstream promoter activity by both estrogen and GnRH in the ovary
Chiang et al., J Clin Endocrinol Metab 2000
:
Furthermore, our data suggest that the
effects of hCG and
GnRH on
ERalpha and ERbeta expression in hGLCs are mediated in part by activation of PKA and PKC signaling pathways, respectively
Demay et al., Endocrinology 2001
:
Moreover, we show that the
effects of
GnRH on
ERalpha transcriptional activity in gonadotrope cell lines are mediated by the PKC/MAPK pathway
Hu et al., Mol Endocrinol 2008
:
These findings demonstrate that the dual actions of E ( 2 ) on GnRH neuronal membrane excitability, cAMP production, and
GnRH secretion are
mediated by the dose dependent activation of
ERalpha and ERbeta expressed in hypothalamic GnRH neurons
Chen et al., Endocrinology 2009
:
These data demonstrate that
GnRH mediated phosphorylation of
ERalpha in mouse LbetaT2 pituitary cells results in its rapid association with PCAF and the transcriptional activation of fosB, and we demonstrate that this in turn likely activates other genes in pituitary cells including the FSH beta-subunit gene
Davis et al., Biol Reprod 2011
:
The ability of E2 and E2-BSA to increase
GnRH analog binding was
blocked by the
estrogen receptor ( ER ) antagonist ICI 182,780
Dong et al., Mol Cell Endocrinol 1996
:
Evidence for
estrogen receptor mediated regulation of human
gonadotropin releasing hormone promoter activity in human placental cells