Koga et al., Inflammation 2012
(Acute Lung Injury...) :
In these in vitro studies, ETS-GS induced phosphoinositide 3-kinase (PI3K)-Akt phosphorylation and inhibited I?Ba and MAPK phosphorylation
Ghosh et al., J Biol Chem 2012
(MAP Kinase Signaling System...) :
Therefore, based on these observations, it is hypothesized that the activation of PI3K/AKT and p38 MAPK by VEGF results in ETS-1 gene expression, which activates MMP-9 and MMP-13, leading to the invasion and scattering of SKOV-3 cells
Hua et al., American journal of physiology. Renal physiology 2012
:
In these studies, we determined that ANG II induces phosphorylation of ETS-1 via activation of the type 1 ANG II receptor and that Erk1/2 and Akt/PKB phosphorylation are required for these effects