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FGF2 — TAT
Text-mined interactions from Literome
Cavallaro et al., Mol Cell Biol Res Commun 2000
(Cell Transformation, Neoplastic...) :
In light of previous reports on
Tat induced release of
FGF-2 into the extracellular space, our findings may provide an additional mechanism for the observed synergism between Tat and FGF-2 in the pathogenesis of KS
Wu et al., Microvasc Res 2002
(Sarcoma, Kaposi) :
We conclude that ( i ) the response of SC to
Tat is density dependent and ( ii ) the angiogenic effect of Tat on both MEC and SC
requires the presence of
FGF-2
Conaldi et al., Am J Pathol 2002
:
In podocyte cultures
Tat promoted both the transcription and the release of basic
fibroblast growth factor , which contributed to the enhanced cell proliferation
Zhou et al., PloS one 2013
(Cell Transformation, Neoplastic...) :
In an allograft model,
Tat promotes vIL-6 induced tumorigenesis and expression of CD31, CD34, SMA, VEGF,
b-FGF , and cyclin D1
Ensoli et al., Nature 1994
(Acquired Immunodeficiency Syndrome...) :
Synergy is due to
Tat , which enhances endothelial cell growth and type-IV collagenase expression in
response to
bFGF mimicking extracellular matrix proteins