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CTR9 — FGFR3

Text-mined interactions from Literome

Dohi et al., Biochem J 1991 : These results suggest, at least, that the stimulation of a remodelling pathway is involved in the increased PAF synthesis induced by ACh ... However, the activation of both enzymes by ACh was transient, in spite of the fact that ACh stimulated PAF formation was continuous
Sánchez et al., Am J Physiol Heart Circ Physiol 2006 : While ACh causes only vasodilation, PAF induces vasoconstriction and hyperpermeability
Cheng et al., J Pharmacol Exp Ther 2006 (Esophagitis) : The inhibition was reversed by the platelet activating factor (PAF) antagonist CV3988 [ ( +/- ) -3- ( N-octadecylcarbamoyl ) -2-methoxy ) propyl- ( 2-thiazolioethyl ) phosphate ], whereas the PAF analog 2-O-methyl platelet activating factor C-16 (PAF-16) inhibited EFS induced contraction and acetylcholine (ACh) release in circular muscle strips ... Release of PAF by the mucosa inhibits ACh release from circular muscle layer neurons and initiates sequential formation of inflammatory mediators in muscle, resulting in production of PAF by the muscle itself, possibly initiating in a self sustaining cycle
Komatsu et al., Eur J Pharmacol 1990 : OKY-046.HCl ( 30-100 mg/kg, intraduodenally ( i.d. ) or orally ( p.o. ) ) suppressed dose dependently the airway hyperresponsiveness to acetylcholine (ACh) induced by formyl-methionyl-leucyl-phenylalanine ( FMLP ), platelet activating factor (PAF) and repetitive antigen
Bussolino et al., J Lipid Mediat 1989 : In previous work we showed that platelet activating factor (PAF) was produced upon stimulation of the chick retina with acetylcholine (ACh) and dopamine ( DA ), via a dithiothreitol-insensitive cholinephosphotransferase ( DTT-CPT ) ... Since ACh and DA stimulated PAF production at different stages of development, we advanced the hypothesis that selected cholinergic and dopaminergic receptors were involved
Bussolino et al., J Biol Chem 1986 : PAF produced in response to ACh , dopamine, or A23187 was not released into supernatants but was extractable from retinas
Wang et al., J Neurochem 1994 : PAF inhibited K+ depolarization induced [ 3H ] ACh release in slices of brain cortex and hippocampus by up to 59 % at 10 nM but did not inhibit [ 3H ] ACh release in striatal slices ... PAF induced inhibition of [ 3H ] ACh release was blocked 90 +/- 3 and 86 +/- 2 % by pertussis toxin and by anti-G alpha i1/2 antiserum incorporated into cortical synaptosomes, respectively ... The results suggest that PAF inhibits depolarization induced ACh release in brain slices via a G alpha i1/2 protein mediated action and that PAF may serve as a neuromodulator of brain cholinergic system