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FOS — LEP

Text-mined interactions from Literome

Elias et al., Neuron 1999 (Body Weight) : In contrast, leptin induced both Fos and SOCS-3 expression in POMC neurons, many of which also innervated the LHA
Elias et al., J Comp Neurol 2000 : In addition, leptin induced Fos-IR was found in several nuclei of the brainstem, including the superior lateral and external lateral subdivisions of the parabrachial nucleus ( slPB and elPB, respectively ), the supragenual nucleus, and the nucleus of the solitary tract (NTS) ... In the Arc and DMH, leptin induced Fos-IR was observed in neurons that expressed neurotensin mRNA
Bendinelli et al., Mol Cell Endocrinol 2000 : Leptin activates Stat3, Stat1 and AP-1 in mouse adipose tissue ... AP-1 binding activity was also induced in adipose tissue by in vivo leptin treatment with a time course that suggests a post-transcriptional inductive mechanism
Emond et al., Physiol Behav 2001 : Within the nucleus of the solitary tract (NTS), leptin alone did not stimulate c-Fos but significantly elevated the number of c-Fos positive cells in response to intragastric Ensure at medial and rostral levels ... Within the paraventricular nucleus ( PVN ), both leptin and the gastric load stimulated c-Fos expression, but the combination resulted in significantly greater number of c-Fos positive cells
Elmquist et al., Physiol Behav 2001 (Body Weight) : In contrast, leptin induced both Fos and SOCS-3 expression in POMC neurons, many of which also innervated the LHA
Blevins et al., Am J Physiol Regul Integr Comp Physiol 2004 : Injections of fluorescent cholera toxin B into the NTS labeled a subset of pPVN oxytocin neurons that expressed Fos in response to 3V leptin ... OVT resulted in a significant 37 % decrease ( P < 0.05 ) in the potentiating effect of leptin on CCK activation of mNTS neuronal Fos expression
Oliveira et al., Regul Pept 2005 : Fragment Ac- [ Ser117 ] Lep116-140-NH2 ( V ) induced Fos-ir in hypothalamic nuclei that express leptin receptor long form
Fu et al., Cell 2005 : Partially antagonizing this inhibitory loop, leptin also upregulates AP-1 gene expression, which promotes cyclin D1 expression, osteoblast proliferation, and bone formation
Huo et al., Diabetes 2006 : In addition, leptin does not induce c-Fos expression in NTS POMC neurons unlike ARC POMC neurons
Frontini et al., Brain Res 2008 : Interestingly, leptin also increased P-STAT3 and c-Fos immunoreactivity in a distinctive and transient ( from P5 to P13 ) cell population found in the dorsal part of the third ventricle and in subependymal position
Maletínská et al., BMC neuroscience 2008 (Thinness) : This study is based on previously found synergistic effect of leptin and CCK on food intake and our hypothesis on a co-operation of the CART peptide and CCK in food intake regulation and Fos activation in their common targets, the nucleus tractus solitarii of the brainstem ( NTS ), the paraventricular nucleus ( PVN ), and the dorsomedial nucleus ( DMH ) of the hypothalamus
Wang et al., Gastroenterology 2009 (Disease Models, Animal...) : Leptin potentiated signal transducer and activator of transcription 3, AKT, and extracellular signal related kinase 1/2 phosphorylation in KCs and increased AP-1 and nuclear factor-kappaB DNA binding
Caquineau et al., J Neuroendocrinol 2010 : Leptin injected alone significantly increased Fos expression in the arcuate nucleus but had no effect on Fos expression in the VMH, DMH, SON, PVN, AP or NTS compared to vehicle ... Unexpectedly, there was significantly less Fos expression in the PVN and SON of fasted rats injected with leptin and CCK than in rats injected with vehicle and CCK, suggesting that leptin attenuated CCK induced Fos expression in the SON and PVN
Williams et al., J Neurosci 2010 : Leptin induced Fos activity within arcuate POMC neurons was localized separate from POMC neurons that express insulin receptor
Qi et al., Endocrinology 2010 : HPD abolished leptin induced expression of Fos in melanin concentrating hormone cells in the LHA and in CRH cells in the PVN
Wang et al., Brain Res 1998 : Leptin did not increase Fos expression in the brain compared with vehicle treated mice ... Devazepide ( a CCK-A receptor antagonist, 1 mg/kg, i.p. ) prevented the increase in Fos expression induced by leptin-CCK in the PVN and by CCK alone in the PVN, CeA and NTS/AP ... Leptin in conjunction with CCK selectively enhanced Fos expression in the PVN