◀ Back to MMP3
FOS — MMP3
Text-mined interactions from Literome
Westermarck et al., FASEB J 1999
(Neoplasm Invasiveness...) :
This review will summarize the current view on the role of MMPs in tumor growth, invasion, and survival, and focus on the
role of mitogen activated protein kinases and
AP-1 and ETS transcription factors in the regulation of
MMP gene expression during invasion process
Bamba et al., J Gastroenterol 2003
:
There findings indicate a
role for
AP-1 and MAP kinases in cytokine induced
MMP-3 secretion
Fleenor et al., Invest Ophthalmol Vis Sci 2003
:
Involvement of
AP-1 in interleukin-1alpha stimulated
MMP-3 expression in human trabecular meshwork cells
Pang et al., Invest Ophthalmol Vis Sci 2003
(Glaucoma, Open-Angle) :
These effects were blocked by sequestering AP-1, suggesting that activation of
AP-1 can
lead to increased
MMP-3 production in the TM, which in turn improves outflow facility
Kajanne et al., J Cell Physiol 2007
:
Here we provide genetic and biochemical evidence that EGF-R- and
AP-1 mediated signals are
required for
MMP expression and collagen contraction in fibroblasts
Oliver et al., J Rheumatol 2007
(Arthritis, Experimental...) :
We evaluated whether a vanadium
AP-1 inhibitor could
reduce MMP expression and subsequent joint damage in CIA
Lin et al., Rheumatol Int 2008
(Chondrosarcoma...) :
Using chondrosarcoma cells stimulated with IL-1beta, the effects of GLN on the mRNA and protein levels of
MMP-3 , the
activation of JNK, ERK, p38, NF-kappaB, and
AP-1 , the nuclear translocation of NF-kappaB/Rel family members, and PI3-kinase/Akt activation were studied
Woo et al., J Neurochem 2008
:
Inhibition of
MMP-3 or -9 significantly
suppressed the expression of iNOS and pro-inflammatory cytokines and the activities of NF-kappaB,
AP-1 , and MAPK in LPS stimulated microglia
Meng et al., Toxicol Lett 2009
:
Mechanistic studies indicate that B [ a ] P-induced transcriptional activation of
MMP-3 is not
mediated by
AP-1 , NF-kappaB
Hasegawa et al., Exp Cell Res 2009
(Neoplasm Invasiveness) :
To assess the role of AP-1 function, we examined the
effects of dominant negative
Fos ( DeltaFos ), BATF and siRNA against c-Jun on
MMP production in v-Crk transformed cells which have augmented production of MMP-2 and MMP-9
Lee et al., J Immunol 2010
:
Inhibition of
MMP-3 or -9 also
suppressed the activities of MAPK, NF-kappaB, and
AP-1
Chambers et al., Exp Cell Res 2013
(Periodontitis) :
Here we show that IL-1 induced binding of transcription factor AP-1 to the
MMP-3 promoter consists primarily of c-Jun, JunB, and c-Fos and that binding of c-Jun and
c-Fos is
inhibited by the combination of cytokines while binding of Jun B is not