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ECM2 — FUT1
Text-mined interactions from Literome
Levy et al., Hepatology 1999
(Carcinoma, Hepatocellular...) :
FAP may contribute to the
HSC induced
extracellular matrix ( ECM ) changes of cirrhosis
Pinzani et al., Semin Liver Dis 2001
(Inflammation...) :
Different groups of soluble factors may be classified according to their prevalent biological effect : ( a ) factors promoting
HSC proliferation and/or migration ( i.e., platelet derived growth factor, basic fibroblast growth factor, insulin-like growth factor-1 ) ; ( b ) factors
promoting fibrillar
ECM accumulation, particularly transforming growth factor-beta1 ; ( c ) factors with a prevalent contractile effect on HSCs, such as endothelin-1, thrombin, angiotensin-II and vasopressin, although all these agents also may promote HSC proliferation ; ( d ) proinflammatory cytokines and chemokines ; and ( e ) cytokines with a prominent antiinflammatory/antifibrogenic activity, such as interleukin-10 and interferon-gamma