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AKT1 — GHSR
Text-mined interactions from Literome
Duxbury et al., Biochem Biophys Res Commun 2003
(Adenocarcinoma...) :
D-Lys-GHRP6 suppressed ghrelin induced proliferation, invasion, and
Akt phosphorylation
Frago et al., J Neuroendocrinol 2005
:
In control rats, immunoreactive pAkt was practically undetectable ; however,
GHRP-6 increased
p-Akt immunoreactivity in the arcuate nucleus, with a subset of neurones also being immunoreactive for NPY
Pazos et al., Vitam Horm 2008
:
At molecular level,
GHSR1a regulates the activation of the downstream mitogen activated protein kinase,
Akt , nitric oxide synthase, and AMPK cascades in different cellular systems
Duran-Prado et al., Circ Res 2013
(Atherosclerosis...) :
Cortistatin inhibited platelet derived growth factor stimulated proliferation of human aortic SMCs via binding to somatostatin receptors ( sst2 and sst5 ) and
ghrelin receptor , induction of cAMP and p38-mitogen activated protein kinase, and
inhibition of
Akt activity