Gene interactions and pathways from curated databases and text-mining

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CSF1 — GPI

Text-mined interactions from Literome

Pixley et al., Mol Cell Biol 2001 : Here we have overexpressed wild-type ( WT ) PTP phi and a phosphatase-inactive ( C325S ) mutant in a macrophage cell line in the presence and absence of CSF-1 ... In the presence of CSF-1 , WT PTP phi induces cell rounding and ruffle formation, while C325S PTP phi has no effect
Lenda et al., J Immunol 2003 (Inflammation...) : CSF-1 is required for M phi proliferation and survival ... We suggest that during renal inflammation, CSF-1 mediates M phi recruitment, proliferation, activation, and, in turn, TEC apoptosis
Bouyer et al., Endocrinology 2007 : Although a rise in intracellular pH ( pH(i) ) has been linked to inhibition of apoptosis, the effect of CSF-1 on pH(i) in osteoclasts has not been reported ... The present study shows that, in the absence of CO ( 2 ) /HCO ( 3 ) ( - ), CSF-1 causes little change in osteoclast pH(i) ... The CSF-1 induced rise in pH(i) is not blocked by 4,4'-diisothiocyanatostilbene-2,2'-disulfonic acid, an inhibitor of HCO ( 3 ) ( - ) transporters but is abolished by removing extracellular sodium
Rubin Kelley et al., Kidney Int Suppl 1994 (Lupus Nephritis...) : These glomerular M phi require CSF-1 to survive and proliferate
Walker et al., Immunol Invest 1993 (Fibrosarcoma) : T-cell reactivity against allogeneic MHC class II molecules was significantly suppressed by tumor bearing host ( TBH ) M phi in the presence of M-CSF
Moore et al., J Immunol 1996 (Lupus Nephritis) : We hypothesized that TNF-alpha enhanced the M phi response to CSF-1 in MRL-lpr mice
Moore et al., J Immunol 1996 (Lupus Nephritis) : We used a gene transfer strategy to deliver CSF-1 into the kidney to evaluate M phi response to CSF-1 ... CSF-1-TEC + BMM phi caused a greater accumulation of M phi in the implant site and interstitium of MRL +/+ than C3H +/+ mice ... We suggest that the response of MRL M phi to CSF-1 is responsible for the notable accumulation of M phi in the MRL-lpr kidney