Gene interactions and pathways from curated databases and text-mining

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GPR27 — LPA

Text-mined interactions from Literome

Lee et al., Am J Physiol Gastrointest Liver Physiol 2009 (Calcium Signaling) : P2Y5 is a G protein coupled receptor that binds and is activated by lysophosphatidic acid (LPA)
Ochiai et al., Eur J Pharmacol 2013 : We have previously reported that an orphan G protein coupled receptor GPR87 was activated by lysophosphatidic acid (LPA) and that it induced an increase in the intracellular Ca ( 2+ ) levels in the CHO cells genetically engineered to express GPR87-Ga16 fusion protein
Hordijk et al., J Biol Chem 1994 : LPA activates its own G protein coupled receptor ( s ) leading to stimulation of phospholipase C and inhibition of adenylate cyclase
Eichholtz et al., Biochem J 1993 : LPA activates a putative G-protein coupled receptor in responsive cells, but the natural source of exogenous LPA is unknown