Gobert Gosse et al., Cell Signal 2005
(MAP Kinase Signaling System) :
Therefore, M-CSF differentiation signaling in myeloid progenitor cells is mediated through persistent MEK activity but it is not strictly dependent upon Grb2-Sos interaction or PI 3-kinase activity
Saleem et al., J Biol Chem 1995
:
In the present studies, we demonstrate that M-CSF also induces direct interaction of PI 3-kinase ( p85 alpha subunit ) with the SH2/SH3 adaptor protein Grb2