Gene interactions and pathways from curated databases and text-mining

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HES5 — VWF

Text-mined interactions from Literome

de Jonge et al., Crit Care Med 2001 (Blood Loss, Surgical) : Dextran, gelatin, and hydroxyethyl starch ( HES ) all can induce a specific decrease of von Willebrand factor and factor VIII : c. Blood coagulation is most impaired by dextran and high molecular weight HES, both associated with increased postoperative blood loss
Treib et al., Thromb Haemost 1997 (Blood Coagulation Disorders) : Of particular importance is the fact that HES with a high in vivo MW affects factor VIII/von Willebrand factor which can lead to an acquired von Willebrand syndrome