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HGS — KDR

Pathways - manually collected, often from reviews:

• NCI Pathway Database Signaling events mediated by VEGFR1 and VEGFR2: HGS (HGS) → VEGFR2 (dimer)/VEGFA (dimer) complex (KDR-VEGFA) (degradation, inhibits)
  Giorgetti-Peraldi et al., Oncogene 2001, Murdaca et al., J Biol Chem 2004, Hasseine et al., Exp Cell Res 2007
  Evidence: mutant phenotype, assay, physical interaction