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HMGCR — IL1A

Text-mined interactions from Literome

Liao et al., J Leukoc Biol 2013 : Recent studies have demonstrated the stimulatory effects of HMG-CoA reductase inhibitors, statins, on IL-1ß secretion in monocytes and suggest a crucial role for isoprenoids in the inhibition of caspase-1 activity
Hardardóttir et al., Lymphokine Cytokine Res 1994 (Inflammation) : TNF or IL-1 increased hepatic HMG CoA reductase mRNA levels by 3.5- and 3-fold, respectively ... TNF + IL-1 increased HMG CoA reductase mRNA levels by 7-fold
Memon et al., Endocrinology 1993 : Moreover, TNF and IL-1 produced a 2.3- and 2.1-fold increase in hepatic HMG-CoA reductase activity, respectively