Gene interactions and pathways from curated databases and text-mining

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ADCY2 — HSPG2

Text-mined interactions from Literome

Nishimura et al., J Reprod Dev 2004 : These results support the hypothesis that the luteotropic action of LH in bovine luteal cells is mediated not only by activation of adenylate cyclase but also by activation of PLC
Nieto-Fernandez et al., Acta Biol Hung 2004 : These processes take place within a few seconds to minutes and involve sudden cytosolic calcium transients, activation of adenylate cyclase or activation of phospholipase C (PLC)
Paris et al., J Biol Chem 1990 : Addition of guanosine 5'-O- ( 3-thiotriphosphate ) ( GTP gamma S ) to intact Chinese hamster lung fibroblasts ( CCL39 ) depolarized by high K+ concentrations results in activation of phosphoinositide-specific phospholipase C (PLC) ( at GTP gamma S concentrations greater than 0.1 mM ), inhibition of adenylate cyclase ( between 10 microM and 0.5 mM ), and activation of adenylate cyclase ( above 0.5 mM )
James et al., Biochem J 1994 : By contrast with mammalian beta-adrenergic receptors, the avian isoform elicits two distinct effector responses, activation of adenylate cyclase and polyphosphoinositide-specific phospholipase C (PLC) leading to the accumulation of both cyclic adenosine monophosphate ( cyclic AMP ) and inositol phosphates
Vouret-Craviari et al., Biochem J 1993 : alpha-Thrombin ( thrombin ), a potent mitogen for CCL39 hamster lung fibroblasts, stimulates phosphoinositide-specific phospholipase C ( PI-PLC ) and inhibits adenylate cyclase via cleavage of a specific G-protein coupled receptor ( TH-R ), recently cloned from human and hamster cells
Iizuka et al., Epithelial Cell Biol 1995 : Thus no evidence for receptor-agonist dependent PLC induced modulation of the adenylate cyclase was obtained in the normal pig epidermis