Gene interactions and pathways from curated databases and text-mining

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IBD3 — IL1A

Text-mined interactions from Literome

Dinarello et al., Dig Dis Sci 1988 (Acute-Phase Reaction...) : Although there are few studies showing an IL-1 effect on the gastrointestinal tract, the multiple biological properties of IL-1 suggest that IL-1 plays a role in inflammatory bowel disease as well as in mediating some of the gastrointestinal changes observed in systemic acute-phase responses
Cominelli et al., Aliment Pharmacol Ther 1996 (Inflammatory Bowel Diseases) : This article will review current progress in understanding the role of Il-1 and Il-1ra in IBD , as well as discuss recently described polymorphisms in the Il-1 gene cluster and their association with UC and CD