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ABL1 — IFI27
Text-mined interactions from Literome
Gesbert et al., J Biol Chem 2000
:
Second, inhibition of
BCR/ABL kinase activity with the Abl tyrosine kinase inhibitor STI571 rapidly
increases p27 ( Kip1 ) levels
Pierce et al., Hematol J 2001
(Leukemia, Myelogenous, Chronic, BCR-ABL Positive) :
This enhanced
BCR/ABL mediated growth inhibition occurred over a range of growth factor concentrations and was
independent of changes in p21 ( Cip1 ) and
p27 ( Kip ) levels
Chu et al., Leukemia 2010
(Leukemia, Myelogenous, Chronic, BCR-ABL Positive) :
Role of
BCR-ABL-Y177 mediated
p27kip1 phosphorylation and cytoplasmic localization in enhanced proliferation of chronic myeloid leukemia progenitors ... These studies show the importance of
BCR-ABL-Y177-AKT mediated
p27 phosphorylation in altered p27 localization and enhanced proliferation and expansion of primary CML progenitors