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Van Drenth et al., J Immunol 2000
:
Using murine T cell hybridomas transfected to express native or mutated forms of CD4, it was determined that IL-16/CD4 induces a p56 ( lck ) -dependent inhibitory signal for CXCR4, which is independent of its tyrosine catalytic activity
Wathelet et al., Eur J Biochem 1987
:
We found that poly ( rI ) .poly ( rC ) and interleukin-1 , activators of the interferon-beta gene and of T lymphocytes respectively, are both able to enhance IFI-56K mRNA accumulation in all cell lines tested
Cruikshank et al., J Immunol 1996
:
The binding of IL-16 to CD4 results in activation of p56 ( lck ), whose adaptor function is essential for the chemotactic response