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CSF1 — IL10
Text-mined interactions from Literome
Frei et al., J Neuroimmunol 1992
:
Here we report that in addition to GM-CSF, murine astrocytes also produce
macrophage (M)-CSF upon
stimulation with tumor necrosis factor alpha,
interleukin-1 and lipopolysaccharides
Li et al., Biochem Biophys Res Commun 2004
:
We show here that
IL-10 in the
presence of
M-CSF and IL-4 triggers the generation of CD14 ( + ) CD16 ( ++ ) cells from highly purified human cord blood ( CB ) and adult blood Mo. CB Mo were more sensitive to this cytokine combination than adult Mo. IL-10 induced CD14 ( + ) CD16 ( ++ ) cells that expressed dendritic cell markers : CD80, CD86, HLA-DR, and CD83 and initiated significantly decreased allogeneic mixed lymphocyte reactions ( MLRs )
Liu et al., Eur J Oral Sci 2006
(Alveolar Bone Loss) :
Interleukin-10 enhanced the expression of OPG and
down-regulated the expression of RANKL and
CSF-1
Svensson et al., J Immunol 2011
:
We also used a gene array with 420 M-related genes, of which 100 were previously reported to be regulated in a global gene expression profiling of decidual M, confirming that M-CSF/IL-10 induced M are closely related to decidual M. Taken together, our results consistently point to a central
role for
M-CSF and in particular
IL-10 in the shaping of decidual M with regulatory properties
La Flamme et al., PloS one 2012
:
Instead, we found that derivation culture conditions ( GM-CSF plus IL-3 versus M-CSF ) could explain the different responses of BALB/c and IL-4Ra-/- macrophages, and these cytokines shaped the ensuing macrophage such that GM-CSF plus IL-3 promoted more IL-12 and IL-4 while
M-CSF led to higher
IL-10 production
Gruber et al., J Immunol 1994
:
Both IL-4 and
IL-10 strongly
inhibited M-CSF secretion by anti-CD45/IL-1 beta induced monocytes that was accompanied by decreased M-CSF message levels ... IL-4 and
IL-10 repressed
M-CSF gene transcription but did not affect M-CSF message half-life
Hamilton et al., J Leukoc Biol 1993
:
We demonstrate with elutriation purified human monocytes that, in contrast to lipopolysaccharide, recombinant human
CSF-1 does not
induce secretion of prostaglandin E2,
interleukin-6 (IL-6), IL-1 beta, or tumor necrosis factor alpha, as measured by immunoassay ; however, increased urokinase-type plasminogen activator ( u-PA ) activity in cell lysates and mRNA was observed
Dupuis et al., Biochim Biophys Acta 1996
:
While GM-CSF ( 10 ng/ml ) and
interleukin-1 ( 10 U/ml )
stimulated M-CSF production from monocyte derived macrophages, PAF did not
Bergamini et al., Clin Exp Immunol 1998
(HIV Infections) :
M-CSF increased the
IL-10 response of macrophages to LPS by enhancing both the expression of membrane bound CD14, the protein that serves as LPS receptor, and the sensibility of CD14 expressing cells to LPS stimulation