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IL13 — NOS2

Text-mined interactions from Literome

Heitmeier et al., J Biol Chem 1999 (Insulinoma) : Prolonged STAT1 activation is associated with interferon-gamma priming for interleukin-1 induced inducible nitric-oxide synthase expression by islets of Langerhans
Paludan et al., Eur Cytokine Netw 2000 (Herpes Genitalis) : The results indicate that TNF-alpha, secreted by virus infected macrophages, activates NF-kappa B which impairs the IL-13 mediated inhibition of inducible NO synthase (iNOS) expression
Nédélec et al., Biochem Pharmacol 2001 : In monolayers, interleukin-1beta (IL-1beta) induced COX-2 and NOS II expression in a dose- and time dependent manner, to produce high prostaglandin E ( 2 ) ( PGE ( 2 ) ) and nitrite ( NO ( 2 ) ( - ) ) levels in an apparently coordinated fashion
Knuefermann et al., Circulation 2002 (Inflammation...) : Myocardial tumor necrosis factor, interleukin-1beta (IL-1beta), and NOS2 induction was measured before and 6 hours after LPS challenge
Xiong et al., J Biol Chem 2003 : In addition, interleukin-4 inhibits IFN-gamma induced iNOS gene expression by attenuating the physical interaction of ICSBP with IRF-1
Miljkovic et al., Cell Mol Life Sci 2003 : The role of interleukin-17 in inducible nitric oxide synthase mediated nitric oxide production in endothelial cells
Cattaruzza et al., J Biol Chem 2003 : Interleukin-10 induction of nitric-oxide synthase expression attenuates CD40 mediated interleukin-12 synthesis in human endothelial cells
Miljkovic et al., Cytokine Growth Factor Rev 2004 (Inflammation...) : Inducible nitric oxide synthase activation by interleukin-17
Lee et al., Exp Cell Res 2004 (Bone Resorption) : In this study, we found that TNF-alpha, but not receptor activator of nuclear factor kappa B ligand and interleukin 1, increased the expression of iNOS both at the mRNA and protein levels
Davis et al., Alcohol 2004 : Results from a previous study in our laboratory, in the human A172 astroglial cell line, revealed that induction of iNOS activity by tumor necrosis factor-alpha + interferon-gamma + interleukin-1 beta was inhibited by 24-h exposure to a high ethanol concentration ( 200 mM ), but enhanced by 50 mM ethanol
Paoliello-Paschoalato et al., Cytokine 2005 : On the other hand, IL-13 inhibited iNOS activity in IFN-gamma plus LPS stimulated macrophages
Linehan et al., Free Radic Biol Med 2005 (Colitis, Ulcerative...) : IL-10 and IL-4 but not IL-13 suppressed the NO production and iNOS expression by inflamed tissue and cytokine stimulated noninflamed tissue from patients with ulcerative colitis, whereas the three cytokines suppressed NO production in cytokine stimulated biopsies from controls
Zheng et al., J Biol Chem 2006 (Bone Resorption) : Using murine RAW 264.7 and primary bone marrow cells or osteoclasts formed from them by receptor activator of NF-kappaB ligand ( RANKL ) differentiation, we found that inducible nitric-oxide synthase (iNOS) expression and NO generation were stimulated by interferon (IFN)-gamma or lipopolysaccharide, but not by interleukin-1 or tumor necrosis factor-alpha
Lotz et al., Immunology 2007 : Also, IL-4 or IL-13 led to rapid signal transducer and activator of transcription 6 phosphorylation, diminished inducible NO synthase expression, and enhanced the antagonistic arginase 1 activity
Xu et al., Biochem Biophys Res Commun 2011 (Cardiovascular Diseases...) : Knock-down of RSK1 selectively down regulated interleukin-1ß induced iNOS expression without influencing VCAM-1 expression
Cho et al., J Nutr Biochem 2012 : Effects of physiological quercetin metabolites on interleukin-1ß induced inducible NOS expression
Seo et al., Immunopharmacol Immunotoxicol 2012 (Inflammation) : SPEE treatment significantly inhibited the LPS induced production of NO, prostaglandin E ( 2 ), interleukin-6 , and tumor necrosis factor-a and inhibited the expression of iNOS and COX-2 via attenuation of NF-?B p65 expression
Singh et al., J Biol Chem 1995 : In vitro, interleukin-1 beta and interferon-gamma increased osteopontin mRNA levels in CMEC as well as NOS2 expression in both CMEC and cardiac myocytes
Szabó et al., Eur J Pharmacol 1993 : We investigated the role of interleukin-1 in the induction of a Ca ( 2+ ) -independent nitric oxide ( NO ) synthase by bacterial endotoxin in vivo
Tetsuka et al., Proc Natl Acad Sci U S A 1994 : Cross-talk between cyclooxygenase and nitric oxide pathways : prostaglandin E2 negatively modulates induction of nitric oxide synthase by interleukin 1
Kanno et al., Hypertension 1993 : Induction of nitric oxide synthase gene by interleukin in vascular smooth muscle cells
Flak et al., Am J Respir Crit Care Med 1996 (Asthma...) : The induction of iNOS is most likely due to the cytokine interleukin-1 , which is generated intracellularly in response to TCT ; this cytokine, like TCT, can reproduce the pathology caused by B. pertussis infection
Berkman et al., Immunology 1996 : Interleukin-4 (IL-4) and interleukin-13 (IL-13) but not interleukin-10 (IL-10) inhibited both iNOS mRNA expression and nitrite release in A549 cells
Heitmeier et al., J Biol Chem 1997 : Interferon-gamma increases the sensitivity of islets of Langerhans for inducible nitric-oxide synthase expression induced by interleukin 1
Bogdan et al., J Immunol 1997 : In J774A.1 cells, IL-13 strongly reduced both the mRNA and protein levels of inducible nitric oxide synthase ( iNOS, NOS-2 ), as determined by Northern blot analysis and immunoprecipitation
Kinugawa et al., Circ Res 1997 : Forskolin, interleukin (IL)-6 , tumor necrosis factor (TNF)-alpha, or interferon (IFN)-gamma enhanced the LPS induced iNOS expression