Gene interactions and pathways from curated databases and text-mining

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AKT3 — IL17A

Text-mined interactions from Literome

Cho et al., Immunol Lett 2007 (Arthritis, Rheumatoid) : Moreover PI3K/Akt inhibitor, NF-kappaB inhibitor, and FK506 significantly inhibited IL-15 induced IL-17 production in CD4+ T cells
Venkatachalam et al., Am J Physiol Heart Circ Physiol 2008 (Hyperglycemia) : HG induces phosphoinositide 3- kinase [PI3K ; inhibited by adenoviral ( Ad ) .dominant negative ( dn ) PI3Kp85 ], Akt ( inhibited by Ad.dnAkt1 ), and ERK ( inhibited by PD-98059 ) activation and induces IL-17 expression via PI3K -- > Akt -- > ERK dependent signaling
Gu et al., Molecular cancer 2011 (Carcinoma, Hepatocellular...) : IL-17 induces AKT dependent IL-6/JAK2/STAT3 activation and tumor progression in hepatocellular carcinoma