Gene interactions and pathways from curated databases and text-mining

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Text-mined interactions from Literome

Kushikata et al., Neurosci Lett 2006 (Fever) : PAF and its receptor are found in brain and PAF affects or is affected by the production of sleep promoting cytokines such as interleukin-1
Warringa et al., Blood 1991 : We have investigated the modulatory role of GM-CSF and IL-3 on the platelet activating factor (PAF)- , neutrophil activating factor ( NAF/IL-8 ) -, leukotriene B4 (LTB4)-, N-formyl-methionyl-leucyl-phenylalanine ( FMLP ) -, and human complement factor C5a induced chemotaxis of eosinophils from normal individuals
Wang et al., Mediators Inflamm 1996 : Our previous studies have shown that EsA could reduce the release of platelet activating factor (PAF) from rat macrophages, and inhibit interleukin-1 and interleukin-6 production from routine macrophages
Bussolino et al., Biochim Biophys Acta 1987 : These findings indicate that interleukin 1 induces the PAF synthesis by a deacylation/reacetylation mechanism into human endothelial cells
Saito et al., Int Arch Allergy Immunol 1993 : These results suggest that PAF induces the augmentation of IL-3 production in CBMCs which in turn enhances differentiation into eosinophil-lineage cells
Dupuis et al., Res Immunol 1997 : By contrast, M-CSF ( 1000 U/ml ), GM-CSF ( 100 ng/ml ), IL1, IL3 , IL6 and stem cell factor ( 10 ng/ml ) did not stimulate PAF production