Gene interactions and pathways from curated databases and text-mining

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CCR7 — IL4

Text-mined interactions from Literome

Athanassakis et al., Hum Immunol 2000 : Furthermore, in the presence of IL-4 , CCR3 expression declines from 2 to 8 h of culture to increase again at 24 h, where 50 % of the cell population is expressing the receptors
Seneviratne et al., Immunology 2007 (Dermatitis, Atopic) : Interleukin-4 promotes human CD8 T cell expression of CCR7 ... IL-4 promotes expression of CCR7 , a marker linked to existing models of CD8 ( + ) T cell differentiation
Jiang et al., Chin Med J (Engl) 2009 (Embryo Loss) : Expression of chemokine receptors CCR3, CCR5 and CXCR3 on CD4 ( + ) T cells in CBA/JxDBA/2 mouse model, selectively induced by IL-4 and IL-10, regulates the embryo resorption rate ... This study aimed to observe whether IL-4 and IL-10 may regulate the expression of chemokine receptors CCR3, CCR5 and CXCR3 on CD4 ( + ) T cells in CBA/JxDBA/2 mouse model and to explore the role of CCR3, CCR5, CXCR3 in immune tolerance in pregnancy ... The pregnancy immune tolerance may be induced through selective induction of CCR3, CCR5 and CXCR3 expressions by IL-4 together with IL-10
Wang et al., Thorax 2013 (Asthma...) : However, CCR8 inhibition had no significant effect on allergen induced BAL eosinophilia and the induction of the Th2 cytokines IL-4 , IL-5, IL-13 and mucus levels in BAL