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IFI27 — IL7

Text-mined interactions from Literome

Barata et al., J Exp Med 2004 (Precursor Cell Lymphoblastic Leukemia-Lymphoma) : PI3K activation was mandatory for IL-7 mediated Bcl-2 up-regulation, p27kip1 down-regulation, Rb hyperphosphorylation, and consequent viability and cell cycle progression of T-ALL cells
Nakayama et al., Blood 2009 (Precursor B-Cell Lymphoblastic Leukemia-Lymphoma) : Inhibition of IL-7R signaling or JAK3/STAT5 activity resulted in the induction of p27 ( kip1 ) expression and cell-cycle arrest, accompanied by apoptosis in the leukemia cells