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Text-mined interactions from Literome

Dadke et al., J Biol Chem 2003 : Rat fibroblasts lacking PTP1B expression do not activate Src or Rac in response to insulin and can not reorganize actin
Schliess et al., J Biol Chem 2004 : Involvement of integrins and Src in insulin signaling toward autophagic proteolysis in rat liver ... Insulin increases [ Tyr ( P ) ( 418 ) ] Src , [ Tyr ( P ) ( 397 ) ] FAK, and dual p38 ( MAPK ) phosphorylation by about 2-fold
Rosenzweig et al., Cell Signal 2004 : Insulin caused an immediate stimulation of Src and induced its physical association with both IR and PKCdelta ... PP2 inhibition of Src also decreased insulin induced IR tyrosine phosphorylation, IR-PKCdelta association and association of Src with both PKCdelta and IR
Mehdi et al., Antioxid Redox Signal 2005 : Moreover, H2O2, but not insulin , induced Tyr-418 phosphorylation of Src , which was also suppressed by PP-2
Zhang et al., Am J Physiol Cell Physiol 2006 : Involvement of JAK2 and Src kinase tyrosine phosphorylation in human growth hormone stimulated increases in cytosolic free Ca2+ and insulin secretion
Reinehr et al., J Biol Chem 2010 (Hepatomegaly) : As shown by immunoprecipitation studies, insulin and hypoosmolarity induced a rapid, RGD peptide-, integrin beta1 blocking antibody and PP-2-sensitive association of c-Src with the EGFR
Fujimoto et al., Prog Biophys Mol Biol 2011 (Diabetes Mellitus) : Src inhibitors restore the impaired insulin release and impaired ATP elevation by reduction in ROS production in diabetic islets
Nemoto et al., Am J Physiol Heart Circ Physiol 2011 (Diabetes Mellitus, Type 2...) : The insulin stimulated phosphorylation levels of Src/PDK1/Akt/eNOS , but not of Pyk2, were decreased by PP2 in control and losartan treated GK, but not in GK, aortas
Gupta et al., Hypertension 2012 (Disease Models, Animal...) : Like ouabain, insulin also caused c-Src activation
Feng et al., Biosci Biotechnol Biochem 2012 (Insulin Resistance) : Additionally, it inhibited the insulin stimulated phosphorylation of Src at Tyr416, causing a reduction in the Src mediated phosphorylation of Akt ... Inhibition of Src by PP2 resulted in decreases in insulin stimulated glucose uptake and phosphorylation of Src at Tyr416 and Akt at Thr308 and Ser473
Luttrell et al., Oncogene 1989 : These data suggest that insulin and phorbol ester induce phosphorylation of pp60c-src by distinct protein kinases
Baron-Delage et al., Bull Cancer 1994 (Carcinoma...) : In view of the potent mitogenic effect exerted by insulin in human colonic cells, we used Caco-2 cells transfected with an activated ( Val12 ) human Ha-ras gene or the polyoma middle T ( PyMT ) oncogene, a constitutive activator of pp60c-src tyrosine kinase activity, to investigate the effect of oncogenic p21ras and PyMT/pp60c-src on insulin mitogenic signaling
Baron-Delage et al., J Biol Chem 1994 (Colonic Neoplasms) : Taking advantage of the potent mitogenic effect exerted by insulin in human colonic cells, we used Caco-2 cells transfected with an activated ( Val-12 ) human Haras gene or the polyoma middle T ( PyMT ) oncogene, a constitutive activator of pp60c-src tyrosine kinase activity, to investigate the effect of oncogenic p21ras and PyMT/pp60c-src on insulin mitogenic signaling
Ricketts et al., J Biol Chem 1996 : Functional roles of the Shc phosphotyrosine binding and Src homology 2 domains in insulin and epidermal growth factor signaling
Tsakiridis et al., J Biol Chem 1998 : Under these conditions, insulin induced Ras activation was also abolished, and Grb2 association with the Src and collogen homologous ( Shc ) molecule was inhibited without inhibition of the tyrosine phosphorylation of Shc