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IRF6 — SMC2

Text-mined interactions from Literome

Loppnow et al., Prog Clin Biol Res 1994 : LPS antagonists, such as lipid A precursor Ia or nontoxic LPS of Rhodobacter capsulatus reduced the LPS stimulated IL6 production of EC and SMC and the adhesion of leukocytes to EC, but not the cytokine induced activation
Loppnow et al., Infect Immun 1995 : We thus investigated the role of CD14 for stimulation of vascular SMC by LPS ... Since the vascular SMC did not express endogenous CD14, we investigated the role of human serum derived soluble CD14 ( sCD14 ) for activation of SMC by LPS ... In medium containing human serum, anti-CD14 antibodies inhibited activation of SMC by LPS ... These results show that specific activation of vascular SMC by LPS does not involve binding to endogenous membrane CD14, but that the activation of vascular SMC by LPS is mediated to a great extent by serum derived sCD14
Schönbeck et al., J Immunol 1995 : Although SMC did not express specific binding sites for IL-8, Western blot experiments showed that IL-1 alpha-, TNF-, or LPS stimulated SMC released two major immunoreactive isoforms of IL-8 in a time- and dose dependent manner