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JAK2 — VAV1
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
-
IRef Biogrid Interaction:
VAV1
—
JAK2
(direct interaction, enzymatic study)
Shigematsu et al., J Biol Chem 1997*
-
IRef Biogrid Interaction:
VAV1
—
JAK2
(physical association, affinity chromatography technology)
Shigematsu et al., J Biol Chem 1997*
-
IRef Biogrid Interaction:
VAV1
—
JAK2
(physical association, affinity chromatography technology)
Matsuguchi et al., EMBO J 1995*
-
IRef Hprd Interaction:
VAV1
—
JAK2
(in vivo)
Matsuguchi et al., EMBO J 1995*, Shigematsu et al., J Biol Chem 1997*
-
IRef Ophid Interaction:
VAV1
—
JAK2
(aggregation, confirmational text mining)
Matsuguchi et al., EMBO J 1995*
-
IRef Ophid Interaction:
VAV1
—
JAK2
(aggregation, interologs mapping)
Brown et al., Bioinformatics 2005
Text-mined interactions from Literome
Bartolomé et al., Cancer Res 2006
(Melanoma...) :
Importantly, up-regulation of MT1-MMP expression by CXCL12, a mechanism contributing to melanoma cell invasion, is blocked by knocking down
Vav expression or by
inhibiting Jak
Shigematsu et al., J Biol Chem 1997
:
These results suggest the possible
role of
JAK2 for tyrosine phosphorylation of
Vav and involvement of Vav and PI3-kinase in Epo induced proliferative signals