◀ Back to ABL1
ABL1 — JUN
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Barilá et al., EMBO J 2000
:
Surprisingly, elevated levels of
c-Jun activated nuclear
Abl , resulting in activation of the JNK serine/threonine kinase
Perrotti et al., Mol Cell Biol 2000
:
FUS proteolysis is induced by
c-Jun , is
suppressed by
BCR-ABL or Jun kinase 1, and does not depend on c-Jun transactivation potential, ubiquitination, or its interaction with Jun kinase 1
Mancini et al., Traffic 2009
(Leukemia, Myelogenous, Chronic, BCR-ABL Positive) :
In particular, constitutive tyrosine kinase ( TK ) activity of p210
BCR-ABL blocks
c-Jun N-terminal kinase (JNK) phosphorylation leading to 14-3-3 sigma phosphorylation at a critical residue ( Ser ( 186 ) ) for c-ABL binding in response to DNA damage
Kobayashi et al., Leukemia 2009
(Leukemia, Myeloid, Chronic-Phase) :
BCR-ABL directly
inhibited c-Jun expression, as c-Jun downregulation in primary CML neutrophils and in the CML blast cell lines, KCL22 and K562, was reversed by the tyrosine kinase inhibitor imatinib