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KDR — VAV2

Pathways - manually collected, often from reviews:

• Reactome Reaction: VAV2 → KDR (reaction) Song et al., J Immunol 1999, Aghazadeh et al., Cell 2000, Garrett et al., Exp Cell Res 2007, Deckert et al., Immunity 1996, Teramoto et al., J Biol Chem 1997

Text-mined interactions from Literome

Seye et al., J Biol Chem 2004 (Arteriosclerosis) : Moreover, activation of VEGFR-2 by UTP leads to the phosphorylation of Vav2 , a guanine nucleotide exchange factor for Rho family GTPases
Garrett et al., Exp Cell Res 2007 : Moreover, Vav2 is tyrosine phosphorylated upon VEGF treatment, which temporally correlates with Rac1 activation and requires VEGFR-2 signaling and Src kinase activity