Gene interactions and pathways from curated databases and text-mining

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KL — TCF24

Text-mined interactions from Literome

Izquierdo et al., Nefrologia 2012 (Acute Kidney Injury...) : Interestingly, both TWEAK activation of CXCL16 mRNA transcription and suppression of Klotho mRNA transcription were mediated by the NFκB transcription factor
Izquierdo et al., Nephrol Dial Transplant 2012 (Inflammation...) : Klotho down-regulation may be induced by specific cytokines such as tumour necrosis factor-a or TWEAK through the canonical activation of the inflammatory transcription factor nuclear factor kappa B ( NF?B ) and, specifically RelA