Gene interactions and pathways from curated databases and text-mining

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BCL10 — LEP

Text-mined interactions from Literome

Valerio et al., Stroke 2009 (Anoxia...) : Leptin treatment activated the nuclear translocation of nuclear transcription factors kappaB dimers containing the c-Rel subunit, induced the expression of the antiapoptotic c-Rel target gene Bcl-xL in both control and oxygen-glucose deprivation conditions, and counteracted the oxygen-glucose deprivation mediated apoptotic death of cultured cortical neurons ... Leptin mediated Bcl-xL induction and neuroprotection against oxygen-glucose deprivation were hampered in cortical neurons from c-Rel ( -/- ) mice
Ponemone et al., Clinical and translational gastroenterology 2010 : Leptin and APN inhibited anti-CD3-stimulated-LPL-T apoptosis and potentiated STAT3 phosphorylation, Bcl-2, and Bcl-xL expression in IBD and control mucosa