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IL4 — LEP

Text-mined interactions from Literome

Maruna et al., Vnitr Lek 2001 (Acute-Phase Reaction...) : Leptin mediates at least partly the anorectic effect of the tumour necrosis factor and interleukin 1 during inflammation
Quinton et al., Am J Reprod Immunol 2003 : The effect of leptin on cell growth and on the production of cytokines [Leukaemia Inhibitory Factor (LIF), interleukin 6 and tumour necrosis factor-alpha ] and matrix metalloproteinases ( MMP ) ( MMP2 and MMP-9 ) was also investigated
Frisullo et al., J Clin Immunol 2004 (Multiple Sclerosis, Relapsing-Remitting) : Our data showed that leptin induced tumor necrosis factor-alpha, interleukin-6 , and interleukin-10 production by PBMCs of patients in an acute phase of disease but not in patients in a stable phase or in healthy controls
Chen et al., Neuroscience bulletin 2006 : Moreover, we found that PHA induced IL-4 production by PBMCs of patients in an acute phase of disease, but leptin inhibited this ability of PHA
Orlova et al., Bull Exp Biol Med 2009 : Leptin increased the expression of HLA-DR on T lymphocytes, stimulated the production of TNF-alpha and IL-6, and did not affect secretion of IL-2, IL-4 , and IL-10 by mononuclear leukocytes
Sarraf et al., J Exp Med 1997 (Anorexia...) : IL-10, IL-4 , ciliary neurotrophic factor, and IL-2, cytokines not known to induce anorexia or decrease food intake, had no effect on leptin gene expression or serum leptin levels
Granowitz et al., Biochem Biophys Res Commun 1997 (Inflammation) : When considered in the context of animal studies showing that interleukin-1 and tumor necrosis factor-alpha induce leptin and ob mRNA, these results suggest that pro-inflammatory cytokines induce ob gene transcription in vivo via secondary mediators such as transforming growth factor-beta