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LPO — TNF
Text-mined interactions from Literome
Cheng et al., Shock 2005
:
Thus, Pb increased LPS induced liver damage through PKC and p42/44 MAPK modulation of TNF-alpha and oxidative stress, but modulation of
TNF-alpha did not
affect NO or
LPO in rats
Dudnik et al., Izv Akad Nauk Ser Biol 2007
(Cholestasis, Extrahepatic) :
The synergistic interaction can sharply increase the proapoptotic capacity of each of these factors since
TNFalpha activates SMase and
LPO , SMase activity depends on the LPO rate, while ceramide, an SMase produced secondary messenger of apoptosis, can induce oxidative stress