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IFNG — LY6E

Text-mined interactions from Literome

Dumont et al., J Immunol 1990 : Our data also indicate that IFN-gamma and IFN-alpha/beta induce Ly-6E through overlapping but distinct intracellular pathways with different sensitivities to PKC activators
Altmeyer et al., Cell Immunol 1991 (Lymphoma, T-Cell) : As a model system, we used the YAC T cell lymphoma, in which Ly-6E is normally absent but can be highly induced both at the mRNA and surface protein levels by IFN-gamma or IFN-alpha/beta ... Ly-6E induction mediated by IFN-gamma or IFN-alpha/beta was also enhanced by cotreatment with TNF-alpha or IL-1 alpha, which by themselves had no detectable Ly-6E inducing effect
Altmeyer et al., Int J Immunopharmacol 1991 (Lymphoma, T-Cell) : Unexpected up-regulation of gene expression by cyclosporin A and FK-506 in a T-cell lymphoma : both immunosuppressants augment Ly-6E antigen induction by interferon-gamma in the presence of ionomycin ... Therefore, through mechanisms apparently related to those involved in their immunosuppressive action, both CsA and FK-506 convert the negative effect of ionomycin on IFN-gamma mediated Ly-6E induction into an overall positive effect
Dumont et al., Cell Immunol 1991 (Lymphoma, T-Cell) : Interestingly, these effects depended on whether Ly-6E induction was mediated by IFN-gamma or IFN-alpha/beta
Khodadoust et al., Blood 1998 (Lymphoma, B-Cell) : Distinct regulatory mechanisms for interferon-alpha/beta ( IFN-alpha/beta ) - and IFN-gamma mediated induction of Ly-6E gene in B cells ... The murine Ly6-E gene is transcriptionally induced by interferon-alpha/beta ( IFN-alpha/beta ) and IFN-gamma in a variety of distinct cell types